S.A.R.Ms, or selective androgen receptor modulators, are a unique class of molecules that are being developed to treat diseases that are currently being treated with AAS (anabolic-androgenic steroids). Some S.A.R.Ms have even gone to trial for TRT (testosterone replacement therapy).
When S.A.R.Ms bind to the receptor they demonstrate anabolic and hypertrophic activity in both muscle and bone. This makes them ideal candidates for TRT, osteoporosis treatment and muscle wasting treatment.
For bodybuilders, S.A.R.Ms provide the benefits of traditional AAS (anabolic-androgenic steroids) - more muscle, less fat, and better bone density - while producing significantly fewer unwanted side effects (estrogen related sides and water retention).
S.A.R.Ms can have an anabolic to androgenic ratio as high as a 10:1. This is what allows them to build muscle with little to no side effects. They also typically display a high bioavailability, ensuring effective utilisation and absorption.